Table 3 Expression of E4 in relation to HPV status

From: HPV E4 expression and DNA hypermethylation of CADM1, MAL, and miR124-2 genes in cervical cancer and precursor lesions

 

Total

HPV positive

HPV negativea

Extensive E4

Focal E4

E4 negative

n

%

n

%

n

%

n

CIN grading

No dysplasia

35

–

–

–

–

7

100

28

CIN1

19

6

50.0

1

8.3

5

41.7

7

CIN2

17

3

18.8

4

25.0

9

56.3

1

CIN3

22

3

16.7

4

22.2

11

61.1

4

Carcinoma

22

–

–

5

22.7

17

77.3

–

  1. CIN cervical intraepithelial neoplasia; HPV human papillomavirus
  2. aNo E4 expression was observed in HPV negative lesions
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