Fig. 4 | Modern Pathology

Fig. 4

From: Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas

Fig. 4

A colonic adenocarcinoma showing diffuse tumor cell positivity for PD-L1. H&E section shows that the tumor grows in irregular sheets and nests (A). Single antibody PD-L1 stain shows diffuse positivity in the tumor cell nests (B). Double-antibody immunohistochemistry (PD-L1 + SATB2) further confirms that the SATB-2 positive cells, i.e., tumor cells, have clearly demonstrable PD-L1 labeling (red chromogen) (C)

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