Fig. 6 | Modern Pathology

Fig. 6

From: Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas

Fig. 6

Correlation between immune cell PD-L1 expression at invasive front and tumor-infiltrating lymphocyte count (A and B). A positive correlation is demonstrated in mismatch-repair-deficient tumors (groups A–C, p < 0.001), but not in mismatch-repair-proficient tumors (groups D and E, respectively). Designations for the groups: A, mismatch-repair-deficient—Lynch syndrome associated; B, mismatch-repair-deficient—unexplained C, mismatch-repair-deficient—MLH1-methylated; D, mismatch-repair-proficient—tumor-infiltrating lymphocyte-high; E, mismatch-repair-proficient—consecutive

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