Fig. 1 | Modern Pathology

Fig. 1

From: MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification

Fig. 1

MYOD1-mutant rhabdomyosarcoma with sclerosing and spindle cell morphology. a–c Case 4 showing areas with sclerosing morphology with small clusters of spindle cells in a sclerotic background (a), immunohistochemical stains for desmin showing cytoplasmic positivity (b) and MYOD1 showing strong diffuse nuclear positivity (c). d–f Case 21 showing spindle cell morphology with intersecting fascicles of monomorphic fusiform cells (d), immunohistochemical stains for desmin with strong cytoplasmic positivity (e), and MYOD1 showing diffuse nuclear positivity (f)

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