Fig. 2 | Modern Pathology

Fig. 2

From: MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification

Fig. 2

MYOD1-mutant rhabdomyosarcoma with primitive round to spindle cell component. a–c Case 1 showing areas of classic spindle cell morphology with fascicular growth (a), solid zones of primitive appearing spindle cell component (b) and geographic necrosis (MPNST-like); d–f Case 28 showing tumor in the liver with undifferentiated primitive round cell component (d, e) and areas of spindling (f); g–i Case 23, a post-therapy resection, showing primitive round cell areas (g), spindle cell morphology (h) and areas with sclerosing morphology (i). (H&E stains)

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