Fig. 3 | Modern Pathology

Fig. 3

From: MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification

Fig. 3

Morphologic spectrum of MYOD1-mutant rhabdomyosarcoma following therapy. a–c Case 4 showing sclerosing areas on the pre-therapy biopsy (a), while in the post-therapy resection (b, c) showing pure spindle cell morphology; d–f Case 12 showing a sclerosing morphology in the pre-therapy biopsy (d), while the post-therapy resection reveals a spindle cell morphology (e) and areas of maturation with rhabdomyoblastic morphology (f); g–i Case 24 showing spindle cell morphology on pre-therapy biopsy (g), while post-therapy resection shows cellular spindle cell areas (h) and areas of maturation (i). (H&E stains)

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