Table 2 Biochemical recurrence-free survival and variables in ISUP Grade (n = 1000)

From: Integrating tertiary Gleason pattern 5 into the ISUP grading system improves prediction of biochemical recurrence in radical prostatectomy patients

Multivariate

Variables

Category

Hazard ratio

95% Lower

95% Upper

P value

ISUP Grade

Grade 1

1

   

Grade 2

1.24

0.719

2.139

0.439

Grade 3

2.68

1.53

4.694

0.0006

Grade 4

6.118

3.246

11.532

<0.0001

Grade 5

5.324

2.937

9.652

<0.0001

Age

65>

1

   

65≦

1.03

0.781

1.358

0.8353

Clinical T

cT2

1

   

cT3

0.881

0.458

1.696

0.7048

Pathological T

pT2

1

   

pT3

1.315

0.989

1.748

0.0597

Margin status

Negative

1

   

Positive

3.135

2.351

4.181

<0.0001

PSA

Continuous

1.027

1.017

1.037

<0.0001

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