Table 4 Biochemical recurrence-free survival and variables in ISUP Grade with integrating tertiary Gleason pattern 5 (n = 1000)

ISUP Grade

Grade 1

1

Grade 2 without tertiary Gleason pattern 5

1.142

0.654

1.994

0.6412

Grade 2 with tertiary Gleason pattern 5

1.858

0.957

3.607

0.0672

Grade 3 without tertiary Gleason pattern 5

2.233

1.222

4.08

0.009

Grade 3 with tertiary Gleason pattern 5

3.537

1.928

6.488

<0.0001

Grade 4

6.296

3.342

11.86

<0.0001

Grade 5

5.618

3.098

10.186

<0.0001

Age

65>

1

65≦

1.02

0.773

1.346

0.8877

Clinical T

cT2

1

cT3

0.946

0.504

1.776

0.8637

Pathological T

pT2

1

pT3

1.243

0.934

1.653

0.1358

Margin status

Negative

1

Positive

3.139

2.354

4.186

<0.0001

PSA (ng/ml)

Continuous

1.025

1.015

1.035

<0.0001