Table 6 Criteria to distinguish a CD30+lymphoproliferative disorder from lymphoma

From: Breast implant-associated anaplastic large cell lymphoma: a review

 

Lymphoproliferative Disorder

Lymphoma

Spontaneous Regression

Common

Rare

Architecture

Preserved

Destroyed

Cytology

Bland to anaplastic

Anaplastic

Immunophenotype

Preserved T-cell antigens

“Loss of T-cell antigens”

Clonality (TRB, TRG)

Sometimes

Often

Karyotype

Diploid

Complex karyotype