Table 3 Logistic regression analysis for correlation of clinicopathologic characteristics and molecular alterations with IDO1 expression

From: Differential expression of PD-L1 and IDO1 in association with the immune microenvironment in resected lung adenocarcinomas

 

OR

95% CI

P

Male

1.65

0.87–3.13

0.126

Age

0.97

0.94–1.00

0.033

Smoking (≥30 PPY)

1.58

0.82–3.07

0.172

Histologic pattern (acinar vs. non-acinar)

2.42

1.31–4.53

0.005

Nuclear grade (3 vs. 1–2)

1.12

0.56–2.20

0.746

Lymphatic invasion (present vs. absent)

1.01

0.49–2.03

0.976

Vascular invasion (present vs. absent)

1.36

0.62–3.00

0.441

CD8+ tumor-infiltrating lymphocytes (2–3 vs. 0–1)

2.94

1.31–6.64

0.009

CD8+ stroma (>10% vs. ≤10%)

1.71

0.87–3.34

0.118

T-bet+ tumor-infiltrating lymphocytes (2–3 vs. 0–1)

1.26

0.48–3.27

0.638

  1. IDO1 indoleamine 2,3-dioxygenase 1, PPY pack per year, OR odds ratio, CI confidence interval, stroma lymphocytes in the tumor stroma
  2. Bold values are significant P values
Back to article page