Table 2 Patient and tumor characteristics of matched interval and non-interval colorectal cancers (CRC)
Featureb | Interval CRC N = 51 (col %) | Matched non-interval CRCa N = 51 (col %) | P (matched comparison) | |
---|---|---|---|---|
Tumor size at diagnosis (cm) | Median (±IQR) | 3.5 cm (2.5) | 3.7 cm (2.3) | 0.97 |
T stage | ≤T2 | 17 (33) | 16 (31) | 0.55 |
>T2 | 31 (61) | 36 (71) | ||
N stage | 0 | 26 (51) | 28 (55) | 0.84 |
1 | 10 (20) | 17 (33) | ||
2 or above | 8 (16) | 5 (10) | ||
Metastasis at diagnosis | No | 45 (88) | 48 (94) | 0.33 |
Yes | 6 (12) | 3 (6) | ||
Tumor grade | Low | 38 (75) | 34 (67) | 0.39 |
High | 13 (25) | 17 (33) | ||
Lymphovascular invasion | No | 36 (71) | 32 (63) | 0.35 |
Yes | 12 (24) | 18 (35) | ||
Mucinous differentiation | No | 35 (69) | 41 (80) | 0.59 |
Yes | 12 (24) | 10 (20) | ||
Medullary differentiation | No | 45 (88) | 49 (96) | 0.57 |
Yes | 2 (4) | 1 (2) | ||
Signet-ring cell differentiation | No | 44 (86) | 49 (96) | 0.66 |
Yes | 3 (6) | 2 (4) | ||
Loss of MMR IHC expressionc | No | 41 (80) | 41 (80) | 1.00 |
Yes | 10 (20) | 10 (20) | ||
Current folate user at time of diagnosis | No | 47 (92) | 50 (98) | 0.57 |
Yes | 2 (4) | 1 (2) | ||
Current aspirin user at time of diagnosis | No | 32 (63) | 36 (71) | 0.40 |
Yes | 18 (35) | 15 (29) | ||
Smoker at time of diagnosis | No | 26 (51) | 25 (49) | 1.00 |
Past | 21 (41) | 15 (29) | ||
Current | 1 (2) | 7 (14) |