Table 3 Characteristics of colorectal cancer (CRC) with loss of MMR expression by immunohistochemistry

From: Clinicopathologic and genetic characteristics of interval colorectal carcinomas favor origin from missed or incompletely excised precursors

Parameter

Interval CRC N = 10 (col %)

Matched non-interval CRC N = 10 (col %)

Age (yrs): mean (SD)

77 (6.6)

77 (8.5)

Gender

  

   Male

0 (0)

3 (30)

   Female

10 (100)

7 (70)

Tumor location

  

   Right colon

9 (90)

9 (90)

   Left colon

1 (10)

1 (10)

Tumor stage

  

   ≤pT2

4 (40)

3 (30)

   ≥pT3

6 (60)

7 (70)

Aberrant MMR immunohistochemical profile

  

   Loss of MLH1/PMS2

7 (70)

9 (90)

   Loss of MSH2/MSH6

3 (30)

1 (10)