Table 3 Characteristics of colorectal cancer (CRC) with loss of MMR expression by immunohistochemistry
Parameter | Interval CRC N = 10 (col %) | Matched non-interval CRC N = 10 (col %) |
|---|---|---|
Age (yrs): mean (SD) | 77 (6.6) | 77 (8.5) |
Gender | ||
Male | 0 (0) | 3 (30) |
Female | 10 (100) | 7 (70) |
Tumor location | ||
Right colon | 9 (90) | 9 (90) |
Left colon | 1 (10) | 1 (10) |
Tumor stage | ||
≤pT2 | 4 (40) | 3 (30) |
≥pT3 | 6 (60) | 7 (70) |
Aberrant MMR immunohistochemical profile | ||
Loss of MLH1/PMS2 | 7 (70) | 9 (90) |
Loss of MSH2/MSH6 | 3 (30) | 1 (10) |