Fig. 1
From: Legumain is an independent predictor for invasive recurrence in breast ductal carcinoma in situ
a Normal breast ductolobular unit (×20) shows negative staining of legumain. b Negative legumain expression (×20) in a pure DCIS case. c Strong expression of legumain in tumor cells and surrounding fibroblasts (×20) in a pure DCIS case (inset: high power view showing the granular pattern of legumain expression). d High expression of legumain in the fibroblasts surrounding DCIS case (×40). e Expression of legumain in a mixed case (×40) showing strong staining in invasive component either within the tumor cells or surrounding stromal fibroblasts
