Fig. 3
From: Legumain is an independent predictor for invasive recurrence in breast ductal carcinoma in situ

Kaplan–Meier curves show that high expression of legumain within the tumor epithelial cells is associated with shorter ipsilateral local recurrence-free interval in the whole series (a), and in breast-conserving surgery (BCS) without adjuvant radiotherapy (b). High expression also showed an association with shorter local recurrence-free interval as invasive disease in the whole series (c) and in patients treated with breast-conserving surgery without adjuvant radiotherapy (d)