Table 4 Mutational profiles
Cases | Mutations | CNAa loss | CNAa gain | Amplifications |
|---|---|---|---|---|
TC1 | CBL, RASA1 | Chromosome 9 | Chromosome 17 | |
TC2 | KMT2C b , ERBB2, ERCC2, TET2, MED12, MTOR, TRAF2, DAXX | Chromosome 9 | Chromosome 17 | MDM2 (12q14.3-q15)b CDK4 (12q14)b |
TC3 | PMS2b, RAD21b, STAT5A, NOTCH2, PLK2 | Chromosome 9 | Chromosome 17 | |
TC4 | KMT2C b | Chromosome 9 | Chromosome 17 | |
TC5 | KDM5C b , TP53 b | Chromosome 9 | Chromosome 17 | |
TC6 | Not detected | Chromosome 9 | Chromosome 17 | |
TC7 | Not detected | Chromosome 9 | Chromosome 17 | |
TC8 | NOTCH3 | Chromosome 9 | Chromosome 17 | |
TC9 | KDM5C b , FBXW7 b , KEAP1 b , DNMT3A, ERBB2 | Chromosome 9 | Chromosome 17 |
