Fig. 1 | Modern Pathology

Fig. 1

From: Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation

Fig. 1

Comparison between age-related lobular involution and hyaline fibrous involution. a Non-involuted breast parenchyma of a premenopausal woman. b, c Age-related lobular involution characterized by terminal duct lobular units with fewer numbers of small acini that have flattened and inconspicuous epithelium along with loss of intralobular stroma. d–f Hyaline fibrous involution characterized by symmetric and regular, periacinar ring-like deposition of basal lamina-like hyaline material in association with atrophic epithelium

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