Table 1 Comparing the proportion of lobules with hyaline fibrous involution (HFI) between groups among the subset of samples with any HFI lobules present

From: Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation

 

BRCA (n = 44)

BBD (n = 14)

p-valuea

HFI-positive lobules/total lobulesb

0.03 (0.004–0.45)

0.08 (0.11)

0.03 (0.01–0.18)

0.05 (0.05)

0.14

HFI-diffuse lobules/total lobulesb

0.02 (0–0.39)

0.06 (0.10)

0.02 (0–0.11)

0.04 (0.04)

0.12

HFI-focal lobules/total lobulesb

0.01 (0–0.10)

0.02 (0.02)

0.01 (0–0.07)

0.01 (0.02)

1.0

  1. BRCA BRCA gene-mutated group, BBD benign breast disease group, HFI hyaline fibrous involution
  2. aBRCA vs. BBD; adjusted for total lobules and age
  3. bValues represent median (minimum–maximum), mean (standard deviation)
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