Fig. 3 | Modern Pathology

Fig. 3

From: MAGE-A expression in oral and laryngeal leukoplakia predicts malignant transformation

Fig. 3

Representative immunohistochemical staining results for MAGE-A in progressing leukoplakia, non-progressing leukoplakia, normal oral mucosa, corresponding tumor specimen and human testis (positive control). a Representative staining result of a progressing D0 leukoplakia (group 1) with MAGE-A expression. b Representative staining result of a progressing D2 leukoplakia (group 1) with MAGE-A expression. c Representative staining result of a non-progressing D3 leukoplakia (group 2) with absent MAGE-A expression. d Representative staining result of normal oral mucosa (group 4) with absent MAGE-A expression. e Representative staining result of a MAGE-A positive corresponding tumor specimen (group 3). f Representative staining result of human testis (positive control) with MAGE-A expression. Nuclear and/or cytoplasmatic staining was considered to indicate positive MAGE-A expression. Illustrations were carried out in ×40 magnification

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