Fig. 4 | Modern Pathology

Fig. 4

From: PD-1 (PDCD1) promoter methylation in Merkel cell carcinoma: prognostic relevance and relationship with clinico-pathological parameters

Fig. 4

Kaplan-Meier survival curves (univariate survival analysis). The only threevariables significantly associated to a higher risk of mortality were mPDCD1high (p = 0.023) and tumor size > 2 cm (p = 0.019) and the absence of Merkel cell polyomavirus (p = 0.001).Milder evidence was found for angioinvasion (p = 0.070), clinical stage III-IV (p = 0.093), absence of immune cells (p = 0.112) and no PD-L1 expression by tumor cells (p = 0.093). mPDCD1 methylation status of PDCD1

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