Fig. 1 | Modern Pathology

Fig. 1

From: Variability in diagnostic threshold for comedo necrosis among breast pathologists: implications for patient eligibility for active surveillance trials of ductal carcinoma in situ

Fig. 1

Pink circles of varying diameter were superimposed onto eight replicate histologic images of a single duct involved by low nuclear grade, solid pattern DCIS to simulate necrosis representing 10–80% of the duct diameter in 10% increments. The images, labeled only 1–8, were circulated to breast pathologists with the question “which image represents the minimum amount of necrosis required for a diagnosis of comedo necrosis?”

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