Table 3 Combined SATB2 and CDX2 immunohistochemistry expression profiles in colon cancer stratified by mismatch repair protein immunohistochemistry and BRAF mutation
From: SATB2 and CDX2 are prognostic biomarkers in DNA mismatch repair protein deficient colon cancer
Feature | SATB2/CDX2 immunoprofile | p-value | ||||
|---|---|---|---|---|---|---|
No. cases | SATB2+/CDX2+ | SATB2+/CDX2− | SATB2−/CDX2+ | SATB2−/CDX2− | ||
Mismatch repair protein | ||||||
Deficient | 144 | 96 (67) | 26 (18) | 13 (9) | 9 (6) | <0.001 |
Proficient | 354 | 300 (85) | 9 (2) | 38 (11) | 7 (2) | |
BRAF mutation | ||||||
V600E mutant | 81 | 52 (64) | 12 (15) | 12 (15) | 5 (6) | <0.001 |
Wild type | 319 | 277 (87) | 12 (4) | 27 (8) | 3 (1) | |
