Fig. 3

a Overall detection of high-grade dysplasia or adenocarcinoma in all low-grade dysplasia patients regardless of flow cytometric results. The detection rates of high-grade dysplasia or adenocarcinoma were 17%, 26%, and 38% within 1, 2, and 7 years, respectively. Each tick represents a patient being censored. b Detection of high-grade dysplasia or adenocarcinoma in low-grade dysplasia patients with abnormal DNA content at baseline. One-, 2-, and 7-year detection rates of high-grade dysplasia or adenocarcinoma in low-grade dysplasia patients with abnormal DNA content were 57%, 86%, and 88%, respectively, whereas 1-, 2-, and 7-year detection rates in low-grade dysplasia patients with normal DNA content were 10%, 10%, and 10%, respectively. Each tick represents a patient being censored