Table 2 Distribution of mutations of the UroSEEK gene panel in invasive bladder cancer

From: Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma

 

pT1 tumors

Muscle-invasive bladder cancer

p-value

UroSEEK genes

101/111 (91%)

40/43 (93%)

0.933

TERTSeqS

80/111 (72%)

27/43 (63%)

0.354

UroSeqS

62/111 (56%)

32/43 (74%)

0.053

FGFR3

21/111 (19%)

5/43 (12%)

0.399

TP53

31/111 (28%)

23/43 (54%)

0.005

PIK3CA

10/111 (9%)

1/43 (2%)

0.273

CDKN2A

5/111 (5%)

7/43 (16%)

0.035

HRAS

3/111 (3%)

1/43 (2%)

1.0

KRAS

3/111 (3%)

0/43 (0%)

0.661

ERBB2

3/111 (3%)

1/43 (2%)

1.0

VHL

4/111 (4%)

0/43 (0%)

0.486

MLL

0/111 (0%)

0/43 (0%)

.

MET

0/111 (0%)

0/43 (0%)

.

  1. Assay categories (UroSEEK and its components) and significant p-value are listed in bold