Fig. 4 | Modern Pathology

Fig. 4

From: An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

Fig. 4

Sessile serrated polyp with dysplasia and correlation with MLH1 loss. a–b Sessile serrated polyp with adenomatous dysplasia (a) is characterized by retention of MLH1 (b). c–f Sessile serrated polyp with minimal deviation dysplasia demonstrating increased complexity in crypt architecture and subtle cytologic abnormalities (c, e). MLH1 immunohistochemistry (d, f) is recommended in order to recognize this morphologic variant

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