Table 4 Colorectal carcinomas associated with serrated precursors

From: An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

Type

CpG methylation

Prognosis

Precursor

Prevalence

BRAF mutated, mismatch repair deficient

+++

Good

Sessile serrated polyp

10–15%

KRAS mutated, mismatch repair proficient

+

Intermediate

Traditional serrated adenoma

Unknown

BRAF mutated, mismatch repair proficient

+++

Poor

Sessile serrated polyp or traditional serrated adenoma

5%

BRAF/KRAS wild-type, mismatch repair deficient

+++

Good

Sessile serrated polyp

5–0%

Back to article page