Fig. 1 | Modern Pathology

Fig. 1

From: Collagen (XI) alpha-1 chain is an independent prognostic factor in breast ductal carcinoma in situ

Fig. 1

Representative photomicrographs of COL11A1 IHC expression. a Normal breast ductolobular unit (×20) shows negative staining of COL11A1 in epithelial cells and occasional staining in the surrounding fibroblasts. b Negative COL11A1 expression (x20) in a pure DCIS case. c Strong expression of COL11A1 in tumor cells and surrounding fibroblasts (x20) in a pure DCIS case. d, e Expression of COL11A1 in a mixed case (x40) showing strong staining in invasive component within the tumor cells and/or surrounding stromal fibroblasts; and (f) negative expression of COL11A1 in a mixed case (×20)

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