Table 1 Comparison of clinicopathological variables of MRI-detectable and undetectable cancers

From: Histological differences in cancer cells, stroma, and luminal spaces strongly correlate with in vivo MRI-detectability of prostate cancer

Variables

MRI-detectability

P value

 

Detectable (n = 35)

Undetectable (n = 24)

 

Age (mean, year)

67

68

0.22

Location (PZ/TZ)

29/6

20/4

0.96

Tumor size (mean, mm)

13

14

0.26

Gleason Grade Group (2/3/4/5)

19/13/1/2

18/5/0/1

0.40

% Gleason pattern 4a

46.4

34.3

0.075

Predominant subtype of Gleason pattern 4 (cribriform/fused/glomeruloid/poorly formed)

6/12/3/14

3/6/0/15

0.25

Time period between biopsy and MRIb (mean, week)

6.0

6.3

0.69

Semiautomatic image analysis

   

  Cancer cells (mean, %)

60.9

42.7

<0.0001

  Stroma (mean, %)

33.8

45.1

0.00089

  Luminal space (mean, %)

5.2

12.2

<0.0001

  1. MRI magnetic resonance imaging, PZ peripheral zone, TZ transition zone
  2. aOnly for tumors with Gleason score 7 (i.e., 3 + 4 or 4 + 3): 32 and 23 cases of MRI-detectable and undetectable cases, respectively
  3. bOnly for cases with post-biopsy MRI: 25 and 12 cases of MRI-detectable and undetectable cases, respectively
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