Fig. 1 | Modern Pathology

Fig. 1

From: Geometric characteristics of collagen have independent prognostic significance in breast ductal carcinoma in situ: an image analysis study

Fig. 1

Diagram shows the different parameters assessed to evaluate the collagen characteristics surrounding DCIS. Green squares refer to the fields of interest for analysis (400 × 400 µm surrounding the DCIS boundary and note that all squares are aligned touching and parallel to imaginary tangential line to the duct boundary. a Perpendicularly arranged collagen fibers relative to duct boundary. b Parallel arranged fibers towards the duct boundary. c Collagen fibers arranged parallel to each other (lower dispersion) while d randomly arranged fibers (higher dispersion). e Dense collagen fibers and f scanty collagen fibers. During the analysis the three parameters were assessed per each field of interest (square) and the final average value was used in the analysis. DCIS ductal carcinoma in situ

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