Fig. 1

Myxoid leiomyosarcoma is characterized by an irregular tumor border (a) and is composed of atypical hyperchromatic spindled and ovoid nuclei organized in bundles in a prominent pale myxoid matrix (b), which stains intensely blue with Alcian blue pH 2.5 stain (c). Myxoid leiomyosarcoma may show less prominent degrees of atypia (d) and low mitotic counts. This tumor was strongly and diffusely positive for desmin (e) and caldesmon (f) by immunohistochemistry