Table 2 Frequency of marker expression in ovarian and lower gastrointestinal tumors

From: A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

 

Lower gastrointestinal

Ovarian

Subtype

Total

CRC

Appendiceal

Total

MBOT

MC

N

230

123

107

155

50

105

CK7

Absent (n, %)

186

110

76

4

3

1

80.9

89.4

71.0

2.6

6.0

1.0

Focal (n, %)

26

8

18

10

6

4

11.3

6.5

16.8

6.5

12.0

3.8

Diffuse (n, %)

18

5

13

141

41

100

7.8

4.1

12.1

91.0

82.0

95.2

Present (%)

19.1

10.6

29.0

97.4

94.0

99.0

CK20

Absent (n, %)

30

12

18

28

11

17

13.0

9.8

16.8

18.1

22.0

16.2

Focal (n, %)

38

26

12

60

16

44

16.5

21.1

11.2

38.7

32.0

41.9

Diffuse (n, %)

162

85

77

67

23

44

70.4

69.1

72.0

43.2

46.0

41.9

Present (%)

87.0

90.2

83.2

81.9

78.0

83.8

CDX2

Absent (n, %)

4

1

3

47

7

40

1.7

0.8

2.8

30.3

14.0

38.1

Focal (n, %)

18

12

6

60

20

40

7.8

9.8

5.6

38.7

40.0

38.1

Diffuse (n, %)

208

110

98

48

23

25

90.4

89.4

91.6

31.0

46.0

23.8

Present (%)

98.3

99.2

97.2

69.7

86.0

61.9

SATB2

Absent (n, %)

23

10

13

135

44

91

10.0

8.1

12.1

87.1

88.0

86.7

Focal (n, %)

23

19

4

11

3

8

10.0

15.4

3.7

7.1

6.0

7.6

Diffuse (n, %)

184

94

90

9

3

6

80.0

76.4

84.1

5.8

6.0

5.7

Present (%)

90.0

91.9

87.9

12.9

12.0

13.3

PAX8

Absent (n, %)

224

123

101

85

29

56

97.4

100.0

94.4

54.8

58.0

53.3

Focal (n, %)

0

0

0

52

14

38

0.0

0.0

0.0

33.5

28.0

36.2

Diffuse (n, %)

6

0

6

18

7

11

2.6

0.0

5.6

11.6

14.0

10.5

Present (%)

2.6

0.0

5.6

45.2

42.0

46.7