Fig. 1 | Modern Pathology

Fig. 1

From: Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma

Fig. 1

Pathological features of hybrid oncocytic/chromophobe renal tumors. a Gross image of a solitary hybrid oncocytic/chromophobe renal tumor arising from the superior pole of the kidney and extending into the perinephric adipose tissue. b Hybrid oncocytic/chromophobe renal tumor showing predominantly renal oncocytoma-type architecture at low power (H&E, × 4) with higher power demonstrating chromophobe renal cell carcinoma-like cytological features (inset; H&E, × 40) in the form of nuclear irregularity, atypia, and perinuclear halos. c Hybrid oncocytic/chromophobe renal tumor showing abrupt transition from a renal oncocytoma-appearing area to a chromophobe renal cell carcinoma-appearing area (H&E, × 10)

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