Fig. 3 | Modern Pathology

Fig. 3

From: PAX8–GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid

Fig. 3

Representative micrographs of thyroid neoplasms mimicking hyalinizing trabecular tumors. The figure illustrates a follicular adenoma of trabecular variant (a, 200×), a poorly differentiated thyroid carcinoma (b, 200×), and a Hurthle cell carcinoma (c, 200×) with prominent hyalinization, mimicking hyalinizing trabecular tumors on morphological ground. No membrane Ki67/MIB1 staining was observed, as exemplified here for the case of follicular thyroid adenoma with trabecular features (d, 200×)

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