Fig. 3 | Modern Pathology

Fig. 3

From: Bone marrow morphologic features, MyPRS, and gene mutation correlations in plasma cell myeloma

Fig. 3

Bone marrow fibrosis grading. Fibrosis in bone marrow, highlighted by reticulin staining, were graded as: MF0 = scattered linear reticulin with no intersections, MF1 = loose network of reticulin with many intersections, especially in perivascular areas, MF2 = diffuse and dense increase in reticulin with extensive intersections, and/or associated with focal osterosclerosis and MF3 = diffuse and dense increase in reticulin with extensive intersections and associated osterosclerosis (×400 magnification)

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