Table 5 Histological features in wild type cases and cases with TP53 mutation and/or 17p  loss

From: Bone marrow morphologic features, MyPRS, and gene mutation correlations in plasma cell myeloma

Genetic alteration

Control

TP53 mut only

17p loss only

TP53 mut & 17p loss

Sheet

 

17/109 (16%)

3/11 (27%)

7/14 (50%)

3/5 (60%)

P Value

 

0.3903

0.0063

0.0372

Modified Bartl Grade

1

44 (41%)

5 (46%)

5 (39%)

1 (20%)

2

54 (54%)

6 (55%)

7 (54%)

2 (40)%

3

9 (8%)

0 (0%)

1 (8%)

2 (40%)

P Value

 

0.6034

0.9711

0.037

Mitoses/HPF

 

1.6

2.9

2.1

4.8

P Value

 

0.133

0.4767

0.0068

  1. Note: Comparison of sheet pattern (Fisher’s exact test), Bartl grade (Chi square) and mitotic index (T-test) between wild cases and cases with TP53 mutation and/or 17p  loss were performed
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