Fig. 3
From: Utility of glutamine synthetase immunohistochemistry in identifying features of regressed cirrhosis

a, b Glutamine synthetase immunohistochemistry of regression cases demonstrating positive glutamine synthetase staining around portal tracts. c Glutamine synthetase immunohistochemistry of a cirrhosis case with focal, aberrant glutamine synthetase staining around portal tract. d Glutamine synthetase immunohistochemistry of normal cases demonstrating expected glutamine synthetase staining around central veins, with no positive staining identified around portal tracts. e Glutamine synthetase immunohistochemistry of cirrhosis cases demonstrating complete loss of glutamine synthetase staining with f Masson trichrome highlighting nodular regeneration and fibrosis (demonstrating classic histologic features of cirrhosis)