Table 1 FLT3-internal tandem duplication-positive cases with discordant allelic ratio classification by next generation sequencing and fragment analysis

From: Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis

Allelic ratio by fragment analysis

Allelic ratio by next generation sequencing

FLT3-internal tandem duplication detected by next generation sequencing

Internal tandem duplication size (bp)

1.2

0.4

c.1785_1837+1dup; p.?

54

0.7

0.4

c.1784_1804dup; p.R595_L601dup

21

0.5

0.4

c.1817_1818ins87; p.P606_R607ins29

87

0.5

0.4

c.1770_1793dup; p.Y597_E598ins8

24

0.8

0.4

c.1794_1795ins63; p.E598_Y599ins21

63

0.5

0.4

c.1750_1809dup; p.S584_W603dup

60

0.9

0.3

c.1764_1765ins18; p.E588_Y589insDPYIDP

18

0.5

0.3

c.1827_1828ins81; p.Gly583_Asn609dup

81

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