Table 3 Additional FLT3 mutations identified by next generation sequencing in the 402 dual-tested cases
Fragment analysis results | Next generation sequencing results | Next generation sequencing variant allele fraction |
|---|---|---|
Negative | c.1775T >C; p.V592A | 18% |
Negative | c.1736T >C; p.V579A | 23% |
Negative | c.1735G >A; p.V579I | 43% |
Negative | c.1727T >C; p.L576P | 11% |
Negative | c.1728_1739del; p.Q577_Q580del | 5% |
Negative | c.2516 A>C; p.D839A | 9% |
Positive for D835/I836 mutations | c.2503 G>A; p.D835N | 24% |
c.2504 A>T, p.D835V | 5% | |
c.2028 C>A; p.N676K | 11% |
