Table 1 HHV8-associated lymphoproliferative disorders

From: KSHV/HHV8-positive large B-cell lymphomas and associated diseases: a heterogeneous group of lymphoproliferative processes with significant clinicopathological overlap

HHV8-associated diseases (2017 WHO lymphoma classification)

 Primary effusion lymphoma, classic, and solid variants

 HHV8-positive multicentric Castleman disease

 HHV8-positive diffuse large B-cell lymphoma, NOS

 HHV8-positive germinotropic lymphoproliferative disorder (GLPD)

Other HHV8-related lymphoproliferations

 HHV8-positive reactive lymphoid hyperplasia

 Plasmablastic proliferation of the splenic red pulp

 KSHV/HHV8 inflammatory cytokine syndrome (KICS)

Post-transplant HHV8 infection

 Aplastic marrow with plasmacytosis