Table 3 Differential diagnosis of HHV8 lymphoproliferative disorders presenting as solid masses (typical features)
Location | HIV | EBER | Somatic mutations of the IGH | Monoclonality (IGH) | |
---|---|---|---|---|---|
Solid PEL | Extranodal | Positive | Positive | Yes | Yes |
HHV8 MCD | Nodal | Positive | Negative | No | No |
HHV8 DLBCL | Nodal or extranodal | Positive | Negative | No | Yes |
HHV9 GLPD | Nodal | Negative | Positive | Yes | No |