Fig. 5 | Modern Pathology

Fig. 5

From: Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations

Fig. 5

Focal HMB45-positive pigmented cells in Malignant Spitz tumor with MAP3K8 fusion (same case as Fig. 1a). a Exophytic, mainly dermal proliferation with broad superficial ulceration. b HMB45 stain with foci of strong immunoreactivity against a background of patchy dermal positivity. c Close-up view of HMB45-positive area showing a pigmented aggregates of large epithelioid melanocytes. d HMB45 stain of area c

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