Fig. 1 | Modern Pathology

Fig. 1

From: Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung—a single-center analysis of 354 cases

Fig. 1

Different categories of tumor budding, cell nest size and spread through airspaces. Tumor budding category low (BD1; a, d; case #174), intermediate (BD2; b, e; case #172), and high (BD3; c, f; case #343). Different categories of cell nest size, with cell nests >15 cells (g; case #162), and cell nests 5–15 cells (h; case #126). Exemplary case depicting spread through airspaces (i; case #271). (BD1–BD3: a–c: HE upper panel, d–f: pancytokeratin AE1/AE3 lower panel, overall magnification ×200; cell nest size: g, h: HE, overall magnification ×200; spread through airspaces: i: HE, overall magnification ×50)

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