Table 2 Agreement of tumor budding categories (H&E and AE1/AE3) and kappa statistic (k). P < 0.001

From: Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung—a single-center analysis of 354 cases

 

Pancytokeratin AE1/AE3

K (simple)

K (weighted)

H&E

Low (BD1)

Intermediate (BD2)

High (BD3)

Low (BD1)

89

17

0

  

Intermediate (BD2)

8

44

21

0.69 (0.62–0.77)

0.78 (0.72–0.84)

High (BD3)

0

4

65