Fig. 2: Box plot of percentage of tumor cells expressing mismatch repair proteins by immunohistochemistry. | Modern Pathology

Fig. 2: Box plot of percentage of tumor cells expressing mismatch repair proteins by immunohistochemistry.

From: Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes

Fig. 2

The percentage of tumor cells expressing (a) MLH1, (b) MSH2, (c) MSH6, and (d) PMS2 was in general lower for microsatellite instability-high cases with retained mismatch repair protein expression (right, green) in comparison to microsatellite stable cases (left, red).

Back to article page