Table 2 Comparison of histologic cutoffs points in correlation with clinical evidence of graft-versus-host disease.
From: Evaluation of the lower histologic threshold for gastric graft versus host disease
NIH criteria (≥1 apoptotic body per biopsy fragment) | Maximum apoptotic count of 2 | Maximum apoptotic count of 2 and ≥1 apoptotic body per biopsy fragment | |||||||
---|---|---|---|---|---|---|---|---|---|
P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | |
Evidence of graft-versus-host disease in nongastric gastrointestinal biopsies | 0.15 | 2.4 | 0.8–8.3 | 0.54 | 1.4 | 0.5–3.7 | 0.08 | 3.1 | 0.9–12.1 |
Evidence of extraintestinal graft-versus-host disease (skin or liver) | 0.08 | 2.7 | 0.9–8.4 | 0.40 | 1.6 | 0.6–4.2 | 0.04 | 3.2 | 1.1–10.7 |
Treated for graft-versus-host disease | 0.07 | 4.4 | 1.1–30.2 | 0.03 | 3.9 | 1.2–13.9 | 0.04 | 9.4 | 1.7–176.7 |