Table 2 Comparison of histologic cutoffs points in correlation with clinical evidence of graft-versus-host disease.

From: Evaluation of the lower histologic threshold for gastric graft versus host disease

 

NIH criteria (≥1 apoptotic body per biopsy fragment)

Maximum apoptotic count of 2

Maximum apoptotic count of 2 and ≥1 apoptotic body per biopsy fragment

 

P value

OR

95% CI

P value

OR

95% CI

P value

OR

95% CI

Evidence of graft-versus-host disease in nongastric gastrointestinal biopsies

0.15

2.4

0.8–8.3

0.54

1.4

0.5–3.7

0.08

3.1

0.9–12.1

Evidence of extraintestinal graft-versus-host disease (skin or liver)

0.08

2.7

0.9–8.4

0.40

1.6

0.6–4.2

0.04

3.2

1.1–10.7

Treated for graft-versus-host disease

0.07

4.4

1.1–30.2

0.03

3.9

1.2–13.9

0.04

9.4

1.7–176.7

  1. CI confidence interval, NIH National institute of health, OR odds ratio
  2. Statistically significant p-values are in bold