Fig. 1: CDKN2A expression in a case of invasive vulvar squamous cell carcinoma which was negative in primary tumor and positive in recurrences. | Modern Pathology

Fig. 1: CDKN2A expression in a case of invasive vulvar squamous cell carcinoma which was negative in primary tumor and positive in recurrences.

From: CD274 (PD-L1), CDKN2A (p16), TP53, and EGFR immunohistochemical profile in primary, recurrent and metastatic vulvar cancer

Fig. 1

a Primary tumor (invading tumor edge) hematoxylin and eosin (H&E); b first recurrence H&E; c H&E image of second recurrence; d negative CDKN2A in primary tumor; e positive CDKN2A in 1st recurrence; f positive CDKN2A in 2nd recurrence; g positive TP53 in primary tumor; h positive TP53 in 1st recurrence; i positive TP53 in 2st recurrence.

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