Table 1 Clinical and Histopathologic features of Spitzoid Melanomas.
From: Spitz melanoma is a distinct subset of spitzoid melanoma
Case | Age | Sex | Site | Epidermal hyperplasia | Epidermal effacement | Ulceration | Kamino bodies | Pigmentation (score 0–4) | Solar elastosis | Dermal mitoses (per mm2) | Cytology | Pleomorphism | Breslow depth (mm) | Diameter (mm) | Clinical follow-up |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 4 | Male | Lower leg | Mild | No | No | No | 1 | 0 | 2 | Epithelioid | Moderate to severe | 6 | 2.9 | |
2 | 11 | Female | Right arm | Yes | No | No | No | 3 | 0 | 1 | Epithelioid, spindled | Moderate | 1.8 | 7.5 | |
3 | 11 | Female | Left ear | Yes | Yes | No | No | 1 | 0 | 3 | Epithelioid, spindled | Mild to moderate | 1.1 | ≥2.2 | No recurrence at 34 months |
4 | 13 | Female | Left lateral calf | No | No | No | No | 3 | 0 | 0 | Epithelioid, spindled | Mild | N/A | N/A | |
5 | 13 | Female | Left cheek | Yes | No | No | No | 0 | 0 | 2 | Epithelioid, spindled | Mild | 8.4 | 9.2 | |
6 | 16 | Male | Left posterior upper ear rim | Yes | Yes | No | No | 2 | 0+ | 1 | Epithelioid, spindled | Mild | 1.3 | ≥3.3 | |
7 | 23 | Female | Left medial thigh | Yes | Yes | No | No | 1 | 0 | 3 | Epithelioid, spindled | Moderate | 2.2 | ≥8.9 | |
8 | 26 | Female | Left calf | Yes | Yes | No | No | 1 | 1 | 1 | Epithelioid, spindled | Mild to moderate | 1.2 | 5.3 | |
9 | 27 | Male | Right buttock | Yes | No | No | No | 2 | 0 | 0 | Epithelioid, spindled | Mild | 0.6 | 5.9 | No recurrence at 48 months |
10 | 34 | Male | Right lateral leg | Yes | No | No | Yes | 3 | 0+ | 2 | Epithelioid | Moderate to severe | 1.3 | 5.5 | No recurrence at 36 months |
11 | 39 | Male | Right thigh | Yes | No | No | No | 0 | 2 | 0 | Epithelioid | Severe | 3.7 | 6.9 | |
12 | 47 | Female | Left knee | Yes | Yes | No | No | 0 | 0+ | 8 | Spindled | Mild | 3.8 | 9.9 | No recurrence at 31 months |
13 | 49 | Male | Right lower leg | Yes | No | No | Yes | 4 | 1 | 0 | Epithelioid | Severe | 0.7 | 5.5 | Died after 60 months (unknown reason) |
14 | 50 | Female | Left leg | No | No | No | No | 0 | 1 | 2 | Epithelioid, spindled | Moderate | 1.3 | ≥5.7 | |
15 | 52 | Female | Right proximal forearm | Yes | Yes | No | No | 1 | 2 | 0 | Epithelioid | Moderate | 0.4 | 6.7 | |
16 | 55 | Male | Left lateral back | Yes | No | No | No | 0 | 1+ | 0 | Epithelioid, spindled | Moderate | 0.7 | 7.9 | |
17 | 57 | Male | Right chest | Yes | Yes | Yes | No | 4 | 1 | 1 | Epithelioid | Severe | 0.9 | ≥8.5 | |
18 | 61 | Male | Right thigh | Yes | Yes | No | No | 1 | 2- | 2 | Epithelioid, spindled | Moderate | 1.9 | 4.4 | No recurrence at 36 months, sentinel node negative |
19 | 68 | Male | Left forearm | Yes | Yes | No | No | 0 | 2+ | 5 | Epithelioid | Severe | 1.9 | ≥5.7 | No recurrence at 57 months |
20 | 68 | Male | Right cheek | Yes | Yes | Yes | No | 1 | 3 | 1 | Epithelioid, spindled | Moderate | 1.9 | 4.4 | No recurrence at 34 months |
21 | 69 | Male | Left posterior shoulder | Yes | Yes | No | No | 4 | 1+ | 0 | Epithelioid, spindled | Mild to moderate | 1.1 | 5.5 | Multiple cutaneous recurrences beginning 26 months after diagnosis |
22 | 70 | Female | Right anterior thigh | Yes | No | No | No | 4 | 1+ | 0 | Epithelioid, spindled | Moderate | 0.5 | 5.8 | No recurrence at 54 months |
23 | 75 | Female | Right triceps | No | No | No | No | 3 | 2- | 2 | Spindled | Mild | 1.1 | 3.8 | |
24 | 78 | Female | Left lateral thigh | No | Yes | No | No | 2 | 1- | 4 | Epithelioid | Moderate | 1.1 | 2.6 | No recurrence at 13 months |
25 | 80 | Female | Right cheek | No | Yes | No | No | 2 | 3 | 9 | Epithelioid | Moderate | 5.2 | 9.8 | Local lymph node metastasis detected after 1 month, underwent left neck dissection; No recurrence after 60 months |
