Fig. 3: Distribution of mutations or fusions as detected by targeted sequencing of bone marrow. | Modern Pathology

Fig. 3: Distribution of mutations or fusions as detected by targeted sequencing of bone marrow.

From: Myeloid neoplasms associated with t(3;12)(q26.2;p13) are clinically aggressive, show myelodysplasia, and frequently harbor chromosome 7 abnormalities

Fig. 3

a Distribution of mutations of myeloid neoplasms where t(3;12) was detected initially. b Distribution of mutations of myeloid neoplasms where t(3;12) was detected later in disease course. Each column represents a unique patient with myeloid neoplasm associated with t(3;12)(q26.2;p13) (n = 20). Each row represents a mutated gene or gene fusion identified in at least one patient. Numbers, when present, indicate percentage of variant allele frequency (VAF). Red empty boxes when VAF was unavailable. % = percentage of bone marrow blasts at detection of t(3;12); ND = percentage of blasts at detection of t(3;12) not determined.

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