Table 1 Retrospective studies evaluating the natural history of ductal carcinoma in situ.
From: Diagnosis of ductal carcinoma in situ in an era of de-escalation of therapy
Study | # Benign biopsies examined | # with DCIS (# with follow-up) | Age (years) | DCIS histology | Follow-up (years) | Subsequent invasive carcinoma |
|---|---|---|---|---|---|---|
Eusebi et al. [17] | 9520 | 55 (55) | 24–77 | Comedo and non-comedo | 1–14 | 11 (20%) |
Sanders et al. [18] | 11,760 | 45 (45) | 33–74 | Low grade | 3–42 | 16 (36%) |
Rosen et al. [19] | >8000 | 30 (15) | Not stated | Non-comedo | 1–24 | 8 (53%) |
Collins et al. [20] | 1877 | 13 (13) | 41–63 | Low, intermediate, and high grades | 4–18 | OR 13.5 |
