Fig. 11: MYB in adenoid cystic carcinoma.
From: Novel uses of immunohistochemistry in breast pathology: interpretation and pitfalls
Breast adenoid cystic carcinoma displays dual epithelial and myoepithelial cells arranged in solid, tubular, or cribriform structures (a) and displays strong and diffuse nuclear MYB labeling. B This reflects MYB protein accumulation, most often due to a t(6;9) translocation and MYB-NFIB fusion. Triple negative ductal carcinomas also display tubules, nests, or sheets of basaloid cells (C), but only focal MYB labeling (D).
