Table 1 Comparison of the clinicopathological factors between patients with high and low microvessel densities (MVDs) following hepatic resection of intrahepatic cholangiocarcinoma.
Factors | High MVD (n = 50) | Low MVD (n = 50) | P value |
|---|---|---|---|
Age (years) | 65 (33–82) | 67 (39–87) | 0.424 |
Sex (male/female) | 35/15 | 33/17 | 0.668 |
HBV (+, %) | 4 (8.0%) | 6 (12.0%) | 0.505 |
HCV (+, %) | 5 (10.0%) | 5 (10.0%) | 1.000 |
Albumin (g/dL) | 4.1 (3.2–5.3) | 4.1 (2.9–4.7) | 0.729 |
Total bilirubin (mg/dL) | 0.7 (0.2–1.8) | 0.7 (0.4–8.7) | 0.637 |
ALP (U/L) | 307.0 (127–1344) | 351.5 (125–1337) | 0.143 |
γ-GTP (IU/L) | 76.5 (24–574) | 94.5 (11.7–1071) | 0.508 |
Platelets (×104/μL) | 13.3 (5.2–44.0) | 21.6 (10.4–54.3) | 0.017* |
Total lymphocytes (×103/uL) | 1.5 (0.4–4.0) | 1.4 (0.4–2.8) | 0.391 |
ICG15 (%) | 11.6 (1.9–31.0) | 9.1 (2.3–23.6) | 0.179 |
CEA (ng/mL) | 2.8 (0.0–117.5) | 2.6 (0.4–30.7) | 0.664 |
CA19-9 (U/mL) | 34.9 (0.0–531.9) | 90.4 (0.6–98106) | 0.008* |
Tumor size (cm) | 3.5 (0.5–12.0) | 5.0 (1.7–9.5) | 0.016* |
Tumor localization (peripheral type/perihilar type) | 40/10 | 32/18 | 0.075 |
ICC subtype (n = 72) MF/PI/IG | 38/2/0 | 29/2/1 | 0.426 |
Poor differentiation (%) | 27 (54.0%) | 32 (64.0%) | 0.309 |
Microvascular invasion (%) | 18 (36.0%) | 34 (68.0%) | 0.001* |
Bile duct invasion (%) | 19 (38.0%) | 23 (46.0%) | 0.418 |
Intrahepatic metastasis (%) | 13 (26.0%) | 24 (48.0%) | 0.023* |
Lymph node metastasis (%) | 4 (8.0%) | 19 (38.0%) | <0.001** |
Histological liver cirrhosis (%) | 7 (14.0%) | 4 (8.0%) | 0.338 |
